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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RB1
All Species:
36.67
Human Site:
Y403
Identified Species:
67.22
UniProt:
P06400
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P06400
NP_000312.2
928
106159
Y403
P
S
E
N
L
I
S
Y
F
N
N
C
T
V
N
Chimpanzee
Pan troglodytes
XP_509777
1075
122190
Y550
P
S
E
N
L
I
S
Y
F
N
N
C
T
V
N
Rhesus Macaque
Macaca mulatta
XP_001100383
928
106126
Y403
P
S
E
N
L
I
S
Y
F
N
N
C
T
V
N
Dog
Lupus familis
XP_534118
897
103170
Y372
P
S
E
N
L
I
S
Y
F
N
N
C
T
V
N
Cat
Felis silvestris
Mouse
Mus musculus
P13405
921
105320
Y397
P
S
E
N
L
I
S
Y
F
N
N
C
T
V
N
Rat
Rattus norvegicus
P33568
920
105007
Y396
P
S
E
N
L
I
S
Y
F
S
N
C
T
V
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514098
917
104520
Y394
P
S
E
N
L
I
S
Y
F
N
N
C
T
V
N
Chicken
Gallus gallus
Q90600
921
104417
Y393
P
S
D
T
L
I
A
Y
F
N
N
C
T
V
N
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001071248
903
102339
Y389
P
S
S
N
L
L
V
Y
Y
K
N
C
T
V
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_395096
1006
113492
I410
P
S
E
N
L
L
Q
I
L
N
N
C
S
Q
D
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_790323
774
86478
S260
I
L
L
P
F
I
N
S
I
S
S
E
N
T
N
Poplar Tree
Populus trichocarpa
B9GLX8
1035
114624
F461
P
S
A
Q
L
E
R
F
L
V
S
C
D
K
D
Maize
Zea mays
Q3LXA7
1010
111475
F446
P
S
G
E
L
L
R
F
F
S
A
C
D
K
D
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
86.2
99.3
90
N.A.
90.4
89.7
N.A.
81.3
73
N.A.
53.9
N.A.
N.A.
23
N.A.
26.4
Protein Similarity:
100
86.3
99.5
93
N.A.
94.9
95.1
N.A.
88.2
84.1
N.A.
70.9
N.A.
N.A.
42.9
N.A.
42.6
P-Site Identity:
100
100
100
100
N.A.
100
93.3
N.A.
100
80
N.A.
60
N.A.
N.A.
53.3
N.A.
13.3
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
93.3
N.A.
80
N.A.
N.A.
73.3
N.A.
33.3
Percent
Protein Identity:
22.1
23.2
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
40.4
42.1
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
26.6
33.3
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
46.6
60
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
0
0
8
0
0
0
8
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
93
0
0
0
% C
% Asp:
0
0
8
0
0
0
0
0
0
0
0
0
16
0
31
% D
% Glu:
0
0
62
8
0
8
0
0
0
0
0
8
0
0
0
% E
% Phe:
0
0
0
0
8
0
0
16
70
0
0
0
0
0
0
% F
% Gly:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
0
0
0
0
70
0
8
8
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
8
0
0
0
16
0
% K
% Leu:
0
8
8
0
93
24
0
0
16
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
70
0
0
8
0
0
62
77
0
8
0
70
% N
% Pro:
93
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
8
0
0
8
0
0
0
0
0
0
8
0
% Q
% Arg:
0
0
0
0
0
0
16
0
0
0
0
0
0
0
0
% R
% Ser:
0
93
8
0
0
0
54
8
0
24
16
0
8
0
0
% S
% Thr:
0
0
0
8
0
0
0
0
0
0
0
0
70
8
0
% T
% Val:
0
0
0
0
0
0
8
0
0
8
0
0
0
70
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
70
8
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _